You are cordially invited to participate in the ninth biennial meeting on Mechanisms & Models of Cancer to be held at Cold Spring Harbor Laboratory, New York. The meeting will begin on Tuesday, August 12, 2014, and will conclude with lunch on Saturday, August 16. The specific goal of this conference is to bring together a diverse group of scientists studying various molecular, genetic, biochemical and animal model approaches to the analysis of cancer. Junior and senior researchers will join to discuss their latest research findings and technical approaches toward the analysis of cancer models and mechanisms. The format of the meeting will include morning and evening sessions consisting of eight or nine 15-minute talks per session, selected from the abstracts, principally on unpublished work. In addition, there will be two poster sessions, held in the afternoons. The organizers will decide the suitability of each abstract for oral or poster presentation, but please specify if you prefer a poster.