We are pleased to announce a new Cold Spring Harbor meeting on Genome Engineering: The CRISPR/Cas Revolution, which will begin in the evening of Thursday, September 24, and run through lunch on Sunday, September 27. The specific goal for this meeting is to foster fruitful and creative interactions between researchers interested in applying these systems to genome engineering and related advances in a wide variety of organisms, together with scientists studing the basic biology of CRISPR/Cas and related bacterial defense systems. The meeting will consist of six oral sessions and oneposter session .