You are cordially invited to participate in a new conference on Regulatory & Non-Coding RNAs to be held at Cold Spring Harbor Laboratory. The opening session will begin at 7:30 pm on Tuesday, August 26 and the meeting will end after lunch on Saturday, August 30, 2014. As currently planned, the program will have eight sessions devoted to oral presentations, together with three poster sessions for presentations which cannot be accommodated in the formal sessions. Selection of talks for the oral sessions will be made by the organizers in conjunction with the session chairpersons, from the submitted abstracts.