You are cordially invited to participate in the twelfth biennial meeting on The Cell Cycle which will be held at Cold Spring Harbor Laboratory. The meeting will begin on Tuesday, May 13, 2014, and will conclude with lunch on Saturday, May 17. The specific goal for this meeting is to create a forum in which diverse areas of cell cycle regulation in a broad spectrum of experimental organisms can be openly and critically discussed. Emphasis will be placed both upon areas of traditional interest to the cell cycle field, such as control of G1, DNA replication, checkpoint pathways and mitosis, and on areas of emerging interest and importance, such as the links between cell cycle regulation and development, spindle and chromosome dynamics, and specialized cell cycle states such as quiescence.