The 28th IEEE International Symposium on Computer-Based Medical Systems (CBMS 2015) will be held at the University of São Paulo, at São Carlos and at Ribeirão Preto - Brazil, from June 22nd to 25th, 2015. The symposium is the premier conference for computational medicine, providing a mechanism for the exchange of ideas and technologies between academics and industrial scientists, and attracts a worldwide audience. The scientific program of CBMS 2015 will consist of the General and the Industry track sessions with technical contributions reviewed and selected by an international program committee, as well as keynote talks and tutorials given by leading experts in their fields. This year, CBMS will have a special track, which is the Workshop for Ongoing Projects in Computer-Based Medical Systems (WoP-CBMS), which includes the Research School in Computer-Based Medical Systems. While the first three days of CBMS2015 will be held at USP-Sao Carlos, the last day will be held at USP-Ribeirao Preto. The CBMS 2015 will have a special Industry track aimed at strengthening the relationship between the industry and the academia, motivating the community on pursuing productive partnership between both communities.