The 27th IEEE International Symposium on Computer-Based Medical Systems (CBMS 2014) will be held at the Icahn School of Medicine at Mount Sinai, New York NY, from May 27th to May 29th 2014. Attracting a worldwide audience, CBMS is the premier conference for computational medicine, providing a mechanism for the exchange of ideas and technologies between academic and industrial scientists. The scientific program of CBMS 2014 will consist of technical and poster sessions as well as keynote talks given by leading experts. CBMS 2014 invites original, previously unpublished contributions that are not submitted concurrently to a journal or another conference.