The KSE conference is an open international forum for presentation, discussion and exchange of the latest advances and challenges in research of Knowledge and Systems Engineering. The main objective of the conference is to bring together researchers, academics, practitioners and students not only to share research results and practical applications but also to foster collaboration in research and education in KSE. KSE solicits contributions dealing with any aspects of Knowledge and Systems Engineering. The list of main topics includes (but is not limited to): Natural Language Processing; Multimedia & Pattern Recognition; Evolutionary Learning; Information Security; Biomedical Information Processing; Knowledge Representation and Reasoning; Data Mining & Big Data; Information System Engineering; Knowledge Management; System Engineering; Software Systems Engineering; Web Services; Cloud Computing, Computing Models; Human Machine Interaction