The 2015 Angiogenesis Gordon Conference will present and discuss the very latest research on the cellular principles and molecular regulation of blood vessel formation in development and disease. Recent advances highlight the heterogeneity and plasticity of the endothelial cell population, and this meeting will aim to bridge between disciplines and across the scales of resolution to deliver emerging concepts of how endothelial cells coordinate signalling and behaviour to establish functional tissue-specific capillaries and vascular niche networks. Developmental biology, cell biology, computational biology and biophysical aspects will be collated to illustrate the multiscale, and multiphysics nature of blood vessel morphogenesis. We will also seek to highlight new insights and approaches towards translation of angiogenesis concepts into the clinic, including cancer therapy and instructive organ regeneration. This conference will be designed to stimulate rich interactions between experts, senior and junior faculty, industry, clinicians and basic scientist and importantly provide educational opportunity for students and post-docs.