The 2013 Angiogenesis Gordon Conference will present the latest research on the basic and translational biology of angiogenesis and its functional role in embryonic/organ development and disease states with specific emphasis on cancer progression/metastasis. Mechanistic concepts and molecular details in vascular biology, blood vessel formation, growth, and regression will be covered. Angiogenesis contributes to the emergence and progression of cancer in a complex manner and unraveling the molecular details will have a significant impact on current and future drug development. We also need to determine the composite consequence of angiogenesis inhibition in the setting of cancer in order to provide optimal information to aid therapy development in the clinic. Angiogenesis research will provide better biomarkers to predict and monitor anti-angiogenesis therapy in our patients. This conference is being designed to address the most vital areas pertinent to angiogenesis, seeking to stimulate interactions among the experts and importantly provide invaluable educational opportunity for graduate students, post-doctoral fellows and junior investigators.