IEEE CICARE 2016 is the first Symposium of its kind, and will bring together leading research and clinical scientists, engineers, practitioners, technology and solution providers in healthcare and e-health from around the world to discuss latest advances in the field of computational intelligence applied to solving the growing scale and complexity of problems in these inter-disciplinary domains. This symposium will provide a forum for the presentation of recent results in the theory and practice of computational intelligence in healthcare and e-health systems and services, and there will also be Panel discussions to outline future research directions and challenges.