Advances, developments in computing systems and innovative technologies are fast growing towards more complex, heterogeneous, dynamically scalable, ubiquitous, autonomic, and trustworthy computing systems. The cloud computing technology, as an abstraction of concealed complex infrastructure of virtualized resources and provided as web services, has spurred the grand challenges in computing. The aim of FUSION-2016 workshop is to provide a venue of scientific interaction of grand challenging research areas and development of future infrastructure/platforms of complex network computing system technologies, innovations and applications.