The second edition of Cloudification of the Internet of Things 2016 (CIoT’16) is a conference focusing on the challenges of the Internets of Things while considering the whole architecture based on Cloud solutions. In fact, the latter hosts end-users with their profiles and privileges, applications, flows generated by the IoT and M2M, algorithms processing the huge data of IoT, management system, security solutions, virtualization solutions, Network Function Virtualization, forwarding data based on SDN, etc.