ITiCSE 2016, the 21th Annual Conference on Innovation and Technology in Computer Science Education. The program of the conference will consist of keynote lectures, paper sessions, panels, working groups, tips and techniques, courseware demonstrations, posters, and exhibits. The conference also features opportunities to partake in excursions enabling attendees to see some of the surrounding district and mingle in a less intense and formal environment. The conference will begin with the Working Groups, which convene on the Friday evening of the 8th and commence their sessions on Saturday morning July 9, 2016. They will continue their work until the end of the day on Wednesday July 13, 2016.