The 12th Annual Meeting of the International Academy of Mathematical Chemistry (IAMC) and the 2016 International Conference on Mathematical Chemistry (ICMC 2016) will take place from July 4 to July 8, 2016 in Tianjin, China. The first part of this academic activity is the 12th Annual Meeting of the IAMC, which will be held from July 4 to July 5, 2016. The second part is the ICMC 2016, which will be held from July 6 to July 8, 2016. The arrival date is July 3, 2016, and the departure date is July 9, 2016. The main purpose of this academic activity is to bring together people working in (all aspects of) mathematical chemistry to exchange new ideas and achievements in this field. During the 12th annual meeting, the IAMC members will have discussions on the Academy business, election of new members and nomination of candidates for IAMC members, etc.