This free symposium will bring together leading international experts in organic synthesis, including established scientists and outstanding early career researchers, in order to share expertise and best practice and discuss cutting edge research and applications. In addition, this symposium will also feature some insights and opinions on what challenges there will be in the field of organic synthesis in the next 10~20 years. Young research fellows and students are also encouraged to participate and present flash talks and posters. The symposium is fully supported by the National Natural Science Foundation of China (NSFC) and the Royal Society of Chemistry (RSC), and is hosted by the Shanghai Institute of Organic Chemistry (SIOC), Chinese Academy of Sciences.