IEEE HealthCom 2015 aims at bringing together interested parties from around the world working in the healthcare field to exchange ideas, discuss innovative and emerging solutions, and develop collaborations. eHealth is defined as the cost-effective and secure use of information and communications technologies in support of health and the related fields, including health-care related services, surveillance, literature, education, knowledge and research, both at the local site and at a distance. It will make personalized medicine possible and affordable in the near future. The adoption of e-Health technologies in medical fields creates huge opportunities; however, a number of challenges still need to be addressed to build reliable, secure, and efficient networks or platforms with great flexibility.