The 2015 Medicinal Chemistry Gordon Research Conference will feature talks on the cutting edge of the discipline that include new compounds, targets and technologies that advance the science. Bradley Tait of Proteostasis is putting together the scientific program; please review the 2014 program to see examples of the kinds of topics typically covered at this conference. In addition to the general scientific sessions the conference will culminate with a Special Topics Session organized by Sabine Hadida of Vertex. This session is comprised of late-breaking results on important clinical candidates across therapeutic areas. Finally, the conference will wrap up on Thursday evening with the Keynote address organized by the Chair. We strongly encourage attendees to submit poster presentations as, historically, the poster sessions have been an essential outlet for thoughtful discussion and interaction among the conferees. This year, the poster sessions will be organized by Carolyn Dzierba of Bristol Myers Squibb. The 2015 Medicinal Chemistry GRC will continue a tradition of outstanding science presented in a relaxed atmosphere offering a variety of social activities. Vice-Chair Elect Matthew Marx of Takeda will organize social events for the week, including a hike of Mt. Kearsarge, softball, soccer, kayaking and a golf tournament. Please contact Matt with any questions regarding these activities. As we look forward to another outstanding conference in 2015, on behalf of myself, the Vice Chair and the Vice-Chair elect, we welcome your application and particularly encourage the application from those of diverse scientific backgrounds.