Welcome to 2014 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology This conference will bring together top researchers, practitioners, and students from around the world to discuss the latest advances in the field of Computational Intelligence and its application to real world problems in biology, bioinformatics, computational biology, chemical informatics, bioengineering and related fields. Computational Intelligence (CI) approaches include artificial neural networks and machine learning techniques, fuzzy logic, evolutionary algorithms and meta-heuristics, hybrid approaches and other emerging techniques.