The annual SSDBM conference is an international forum for scholarly discourse on designing, building, analyzing and evaluating scientific and statistical data management systems and applications. This event will bring together leading scientific domain experts, practitioners, application developers and users to exchange cutting-edge insights and experiences, and to inspire future research directions. The conference will feature a rich program of research presentations, invited speakers, panel sessions, and demonstrations of research prototypes and industrial systems that capture the ever-increasing interdependence between data management, statistical methods, and scientific research and applications. In its 25th year, SSDBM will take place in the city of Baltimore, Maryland, between the 29th and 31st of July. Baltimore, nicknamed "Charm City", is a major seaport located in the Mid-Atlantic region of the United States. The city features a vibrant and festive harbor area, many unique neighborhoods and landmarks, and world class attractions and entertainment from museums and galleries to sporting events. Baltimore is home to the Johns Hopkins University and the Johns Hopkins Medical School, an internationally-renowned institution for excellence in medical research, teaching and patient care. As part of the Baltimore-Washington Metropolitan Area, the city offers quick access to the nation's capitol, as well as the Atlantic coast including Annapolis, Ocean City, and the Chesapeake Bay.