As an emerging cross-disciplinary research area, the Cyber Physical System (CPS) is attracting attention worldwide. A Cyber-Physical Systems is a system featuring a combination of computational and physical elements, all of which are capable of interacting, reflecting and influencing each other. Furthermore, social systems are evolving with cyber systems and physical systems along with the popularity of online social networking. With the advent of ubiquitous sensing and networking, future social networks turn into cyber-physical interactions, which are attached with associated social attributes. The emergence of the cyber-physical-social computing will significantly change the way we see the world. In the mean time, the convergence of the physical, cyber, and social spaces will exhibit a variety of complicated characteristics, which brings more open issues and challenges for research communities. The 2013 IEEE International Conference on Cyber, Physical, and Social Computing (CPSCom 2013) will provide a high-profile, leading-edge forum for researchers, engineers, and practitioners to present state-of-art advances and innovations in theoretical foundations, systems, infrastructure, tools, testbeds, and applications for the CPSCom, as well as to identify emerging research topics and define the future. The CPSCom2013 is the 6th edition of the successful series, previously held as CPSCom 2012 (Besançon, France), CPSCom 2011 (Dalian, China), CPSCom 2010 (Hangzhou, China), CyberSocialCom 2009 (Hangzhou, China), and CPSC 2009 (Brisbane, Australia).