International Conference on Smart Systems ICSS 2018 is organized and hosted by the School of Engineering, Ajeenkya DY Patil University, Pune in association with Institute of Research and Journals. The conference will provide an international forum for Engineering Students, Researchers, Engineers, Academicians, and Executives from Industries, Research Institutes and Educational Bodies to share and publicize their research work, developmental activities and innovations on the theme of the conference. The conferences focus on three domains of Smart Systems i.e. Computing, Mobility and Intelligent Systems, and healthcare. The seismic shift towards intelligent systems have radicalized and poised the human-life to witness a dynamic future. While envisioning these changes Bertrand Russell and Isaac Asimov predicted in the last century the surge of creativity of human spirits so as to lead a life of eternal youth with unbelievably less hassles in mundane life. This conference brings together the global thought leaders and innovators to discuss real-world issues, tackle intricate problems and find novel enabling solutions by synthesizing the concept of smart systems and technologies.