The RPP conference series aims at offering a comprehensive overview of current challenges and innovative solutions in recombinant protein production across different cell factories. Special attention is attributed to the comparative physiology of microbial and higher eukaryotic platforms for protein production. The 9th RPP conference will build on the successes of previous meetings, which have attracted steadily increasing numbers of researchers from both academia and the bioprocessing industry. The RPP9 meeting will address four major areas and emerging trends in recombinant protein production of industrial relevance: 

• Host physiology under RPP bioprocess conditions, including gene expression and regulation, translation, protein folding and stability, secretion, stress responses and cellular quality control.

• Cell engineering for RPP, including systems metabolic engineering, synthetic biology tools, and integration of random and rational approaches.

• RPP processes at industrial scale, including challenges in up- and down-scaling, host physiology under bioprocess conditions, downstream processing, bioprocess analysis, product quality control, and the safety status of cell factories.

• Biofabrication of complex protein structures, including multicomplex and multispecific proteins, membrane proteins, and surface display of proteins as well as cell-free technologies.