IcBEST (International Conference on Biomedical and Environmental Sciences & Technologies) is a biennial international meeting with significant impact on biomedical research field worldwide. International Symposium on DNA Damage Response & Human Disease (isDDRHD) was first established by Drs. Xingzhi Xu (Beijing Key Lab of DNA Damage Response) and Zhao-Qi Wang (Aging-Fritz Lipmann Institute), which focused on molecular mechanism of DNA damage response and its clinical translation. The icBEST/isDDRHD-2016 meeting, hosted by College of Life Sciences of Sichuan University, will be held from Oct 14-17 in Chengdu, a beautiful city with rich history and famous Sichuan cuisine.