Advances in computing systems and innovative technologies are fast growing towards developments of more complex, heterogeneous and dynamically scalable computing systems. However, these systems are still vulnerable to system failures or any other untoward incidents. The cloud computing system, as an abstraction of concealed complex infrastructure of virtualized resources to provide cloud services, has spurred the grand challenges in computing. The EDCSTA-2016 is to provide a venue of scientific interaction of grand challenging research areas and developments of emerging dependable infrastructure/platforms of complex network computing system technologies, innovations, and applications.