Healthcare is one of the largest industries with 5-18% of GDPs spent on health and Care globally. The healthcare budgets of the vast majority of nations continue to outgrow their GDPs. Social, demographic, economic and technological factors are the drivers for ever faster changing healthcare models. While the demographic shifts in the populations display significant socio-economic challenges they trigger more and more opportunities for innovators in the areas of sensor technology the Internet of Things, Robotics, e-health, m-Health, Cloud Computing and emerging technologies such as 5G, Big Data, SDNs, NFV, Precision and Personalized Medicine. However, the integration of innovative technology into society is associated with a lot of complexities. Social technological alignment and societal acceptance of technology requires sound solutions with regards to ethical, legal, social and security challenges.