2016 International Symposium on Structural Integrity (ISSI-2016) will be held at Tianjin University, Tianjin, China, during May 26-30 of 2016. The ISSI2016 is the 6th annual symposium on Structural Integrity Series. Before ISSI2016, the ISSI2010 was held at Shanghai in 2010, the ISSI2011 at Hefei in 2011, the ISSI2012 at Jinan in 2012, the ISSI2014 at Lanzhou in 2014, followed by the ISSI2015 at Shenyang in 2015. The predecessor of the annual symposium, Fracture Mechanics (FM) series, took place each year from 2003 to 2009 and was also organized by CSIC. The main theme of ISSI-2016 is “Testing and Evaluation of Structural Integrity”. The purpose of this symposium is hence to bring together the research community and the application community to exchange their new developments and ideas. Besides the traditional fracture and damage mechanics topics, contributions bridging the gap between the mechanics approaches and engineering practices are highly welcome.