The NIH-IEEE Strategic Conference on Healthcare Innovations and Point-of-Care (POC) Technologies for Precision Medicine will focus on defining clinical translation needs and technology solutions. This 2 day conference will facilitate stakeholder – clinicians, healthcare providers, industry experts, innovators, government representatives, researchers and students – participation in key sessions. They include clinical needs for precision medicine, enabling technologies for POC, regulatory issues for POC devices, and sustainable global business models to support POC technologies in resource limited environments. Federal funding opportunities and resources will be showcased, and presentations on recent healthcare innovations, point-of-care technologies, and industry exhibits will be featured. Stakeholders will have the opportunity to discuss barriers and challenges in the broad delivery of accurate and affordable healthcare. Breakout sessions will lead to strategic planning on future directions to enhance resources and collaborations for clinical POC technologies.