Rapid growth in data volume and velocity has driven a revolution in computational infrastructure and processing capabilities, but how does this change the way humans work in this new Big Data environment? Human-centered computing focuses on technologies that enhance the human’s abilities to perceive, understand, and collaborate. There are many significant challenges for combined human/technology systems that emerge from the dramatic changes in the nature of the technology that humans use to harness Big Data. The purpose of this workshop is to gather experts in multi-disciplinary fields and discuss research at the intersection of humans and Big Data. This second workshop on Human-Centered Big Data Research (HCBDR) marks a continuing interest for research that aims to understand how people solve problems and make decisions in the face of magnitudes more information, analyze how tools can help us bridge the gap between Big Data and knowledge acquisition, and evaluate how different aspects of Big Data (e.g., volume, velocity, veracity, and variety) impact a user’s sensemaking strategies and performance.