Data driven scientific discovery is an important emerging paradigm for computing in areas including social, service, Internet of Things, sensor networks, telecommunications, biology, health-care and cloud. Under this paradigm, Data Science is the core that drives new researches in many areas, from environmental to social. There are many associated scientific challenges, ranging from data capture, creation, storage, search, sharing, modeling, analysis, and visualization. Among the complex aspects to be addressed we mention here the integration across heterogeneous, interdependent complex data resources for real-time decision making, streaming data, collaboration, and ultimately value co-creation. Data science encompasses the areas of data analytics, machine learning, statistics, optimization and managing big data, and has become essential to glean understanding from large data sets and convert data into actionable intelligence, be it data available to enterprises, Government or on the Web. Following the first successful edition DSAA'2014 held in 2014 in Shanghai, the 2015 IEEE International Conference on Data Science and Advanced Analytics (IEEE DSAA'2015), sponsored by the IEEE Computational Intelligence Society, aims to provide a premier forum that brings together researchers, industry practitioners, as well as potential users of big data, for discussion and exchange of ideas on the latest theoretical developments in Data Science as well as on the best practices for a wide range of applications. DSAA is also technically sponsored by ACM through SIGKDD. IEEE DSAA'2015 will consist of two main Tracks: Research and Application; the Research Track is aimed at collecting contributions related to theoretical foundations of Data Science and Data Analytics. The Application Track is aimed at collecting contributions related to applications of Data Science and Data Analytics in real life scenarios. DSAA solicits then both theoretical and practical works on data science and advanced analytics. Please note that the 14th International Symposium on Intelligent Data Analysis (IDA) takes place directly after DSAA, on 22-24 October, in St. Etienne, which is within easy reach from Paris by high speed train.