We are honored to inform you that we will hold the 12th International Stereotactic Radiosurgery Society (ISRS) congress in Yokohama from 7th to 11th June in 2015. This biennial congress is one of world’s top meetings regarding cerebral stereotactic radiosurgery and stereotactic body radiation therapy. This will be the first time in 12 years that we will hold the ISRS congress in Japan (last time, under chairman Kintomo Takakura) . In Japan, various medical equipment for stereotactic radiosurgery, such as the Gamma Knife, CyberKnife, Linac radiosurgery and Tomotherapy have been introduced, providing an environment where patients can have many options for tumor treatments, including proton and heavy particle radiotherapy which originated from Japan. In line with these therapeutic methods, related fields such as robotic surgery, navigational surgery, molecular target drugs, immunotherapy, regenerative medicine and children’s treatment under general anesthesia have been continuously evolving. Therefore, I am convinced that now is the right time to make the most of collaboration between these many therapeutic methods. Under the theme of “Meet the Experts and Share the Experiences”, one of the major objectives of this conference is to provide special opportunities wherein not only stereotactic radiosurgery physicians and physicists but also many physicians from related fields can socialize and talk about future treatment strategies, while also discussing the advantages and disadvantages of each field. In addition to conventional plenary sessions and oral and poster presentations, we have two central objectives. They are the “enhancement of educational programs” and the “establishment of debate sessions”. We are planning three official events for overseas guests; Heavy particle center visit, Kabuki theatre, and Ryokan-Mt.Fuji. Through these events, you can experience major advancements in the Japanese scientific field, prominent culture and beautiful historic sites. Yokohama is famous as a birthplace of Western culture in Japan and known internationally as a beautiful harbor city with an exotic atmosphere. Yokohama also provides easy access to airports and bullet trains (Shin-kan-sen), benefiting visitors planning to make a trip to major cities and tourist sites in Japan. We are also planning a family event where you can enjoy Yokohama.