The 2015 Gordon Research Conference (GRC) on Organic Reactions and Processes marks its 62nd anniversary, and will highlight outstanding contributions to synthetic organic chemistry. This year’s conference, co-chaired by Jade Nelson (Pfizer) and Jared Piper (Eli Lilly & Company), will be held at Bates College in Lewiston, Maine from July 19-24th, 2015. This location represents a change in venue for the OR&P GRC, which has been held at Bryant University in Rhode Island for several years. Bates College offers comfortable accommodations, an excellent dining service, a broad range of leisure activities, and a superb New England location within easy access from Portland, ME or Boston, MA. Consistent with the rich history of the Organic Reactions and Processes GRC, the 2015 program is comprised of a unique blend of industrial and academic participants, and includes both established and emerging young investigators from around the world. Our GRC offers the podium to dynamic, world recognized lecturers, and we continue to evolve and stay current in the central science that is chemistry. Diverse topics ranging from total synthesis, organocatalysis and non-precious metal catalysis, to the development of commercial manufacturing processes for active pharmaceutical ingredients will be presented. A session dedicated to emerging topics and novel therapies, such as antibody drug-conjugate development, computational methods, and continuous processing will be included. In addition to the oral lecture program, a series of energizing poster sessions highlighting unpublished work from the laboratories of a large percentage of conference attendees will be featured. A subset of posters from these sessions will be selected to present short oral talks on Thursday morning.