The Chicago Local Section of the American Nuclear Society (ANS) is pleased to host to the 16th International Topical Meeting on Nuclear Reactor Thermal Hydraulics (NURETH-16) at the Hyatt Regency Chicago from August 30–September 4, 2015. Chicago is one of America’s greatest cities, and is one of the most easily accessible destinations in the U.S. for travelers from around the world due to its central location. Chicago has a proven history of hosting past ANS meetings, including the 2012 Annual Meeting. Attendees will be a short distance from Chicago attractions, such as Navy Pier, architectural boat tours, theatrical and musical entertainment and countless dining and shopping options. Building on the foundation of past meetings, including the NURETH-15 in Pisa, Italy, NURETH-16 will invite experts in the field of thermal-hydraulics from around the world to share their research and discuss important issues related to thermal-hydraulics in nuclear reactors. NURETH-16 will also be a venue for organizations to showcase their expertise in nuclear reactor technology, with several opportunities for meeting sponsors to exhibit their products and services the nuclear reactor thermal-hydraulic community.