Over the past 20+ years ISSRE has grown to be recognized as the voice of software reliability. A unique elements that drives its success is the equal mix of a strong research and an equally strong industry program. A rarity among top rated non-profit conferences, which typically have one or the other. ISSRE brings you both - and creates a forum for the discussion of tomorrow's strategies. The 25th annual International Symposium on Software Reliability Engineering (ISSRE 2014) is focused on innovative techniques and tools for assessing, predicting, and improving the reliability, safety, and security of software products. ISSRE also emphasizes industrial relevance, rigorous empirical studies and experience reports on existing software systems.