Contemporary knowledge work environment is creating new kinds of challenges for employees. Experiences of hurry, information overload, fragmentation, loss of control, always-on expectations, attention deficit and burnout are common. One hypothesis for this rise is that hectic rhythms of work, an abundance of information processing needs, the ubiquity of information technology appliances used for work as well as private purposes, and ill-structured working patterns are creating new pressures on human performance. Today’s knowledge worker is typically deeply immersed into the digitally rich, ubiquitous work space during most of the wake hours. Information technology has enhanced knowledge work processes, especially communication related to the work processes, in several ways. But why does this environment cause negative symptoms and disturbances of worker well-being? Or does it cause? If, what could be done to diminish the harmful effects? What is the relation between characteristics of the ubiquitous, immersive, digital work environments and work wellbeing and productivity? Ergonomics is applied multidisciplinary science devoted to the enhancement of fit between human characteristics and tools and environments of the work. It is defined as “(...) scientific discipline concerned with the understanding of interactions among humans and other elements of a system, and the profession that applies theory, principles, data and methods to design in order to optimize human well-being and overall system performance.” (The International Ergonomics Association, 2010). Further, the design target of ergonomics can be either the tools used in the work, the overall work environment characteristics, or the working methods applied in the work. In the case of physical work, the analysis of the details of the work environments and work methods try to detect and control features of the work which create strain, excessive load and risks. For today’s knowledge workers, the focus should not only be on the ergonomic understanding and design of knowledge work, but also on the digital conditions and techniques of knowledge work, especially on the analysis of actual information intensive, digitally embedded work spaces, computing conventions and load exposures created. This new approach to observe, design and enhance digitally rich, ubiquitous, real world work environments and work methods is called information ergonomics. While usability, user experience and HCI research seek to enhance the information technological tools and services to fit better for humans, information ergonomics directs the analytical scrutiny into complete, digitally diverse work environments and actual computing behavior, thereby connecting technological aspects with social ones. Technological aspects to information ergonomics are related for example to hybrid or augmented cognition, machine learning and adaptive technology. The objective of the interactive workshop is to invite researchers with different backgrounds, e.g. computer science, cognitive science, information science, and social science, to build an emerging research agenda for information ergonomics in knowledge, and to share research results and cultivate insights related to it.