We are glad to invite you to the 5th edition of the IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob 2014), the biannual conference on theoretical and experimental issues in the fields of robotics and mechatronics applied to medicine and biology. This year the conference will be held in São Paulo on August 12-15, 2014. The conference theme of this edition is "Biomedical Robotics and Biomechatronics Technology for a World without Borders". The BioRob2014 will share keynote speakers with the XXV Annual Meeting of the Brazilian Society of Physical Medicine and Rehabilitation. Moreover, the State of Sao Paulo will run concurrently and in the same convention center two more events: “Reabilitação” a tradeshow of equipment and technology for rehabilitation and orthopedics, and The VI Meeting of Rehabilitation and Disability Stakeholders involving government representatives, patients, and caregivers. The confluence of all stakeholders engineers, physicians, industry, government, patients, and caregivers will be unique but in line with United Nations 2012 unanimous decision to make healthcare and rehabilitation a human right. BioRob covers both theoretical and experimental challenges posed by the application of robotics and mechatronics in medicine and biology. The primary focus of Biorobotics is to analyze biological systems from a "biomechatronic" point of view, trying to understand the scientific and engineering principles underlying their extraordinary performance. This profound understanding of how biological systems work, behave and interact can be used for two main objectives: to guide the design and fabrication of novel, high performance bio-inspired machines and systems for many different applications; and to develop novel nano, micro-, macro- devices that can act upon, substitute parts of, and assist human beings in prevention, diagnosis, surgery, prosthetics, rehabilitation and personal assistance.