The 2014 Medicinal Chemistry Gordon Conference will feature talks on cutting edge of the discipline that includes new compounds, targets and technologies that advance the science. Lori Gavrin of GlaxoSmithKline is putting together the scientific program; please review the 2013 program to see examples of the kinds of topics typically covered at this conference. In addition to the general scientific sessions the conference will culminate with a Special Topics Session organized by Christopher O’Donnell of Pfizer. This session is comprised of late-breaking results on important clinical candidates across therapeutic areas. Finally, the conference will wrap up on Thursday evening with the Keynote address organized by the Chair. We strongly encourage attendees to submit poster presentations as, historically, the poster sessions have been an essential outlet for thoughtful discussion and interaction among the conferees. This year, the poster sessions will be organized by Brock Shireman of Janssen. The 2014 Medicinal Chemistry GRC will continue a tradition of outstanding science presented in a relaxed atmosphere offering a variety of social activities. Vice-Chair Elect Bradley Tait of Proteostasis will organize social events for the week, including a hike of Mt. Kearsarge, softball, soccer, kayaking and a golf tournament. Please contact Brad with any questions regarding these activities. As we look forward to another outstanding conference in 2014, on behalf of myself, the Vice Chair and the Vice-Chair elect, we welcome your application and particularly encourage the application from those of diverse scientific backgrounds.