Neuronal cell biology has emerged as one of the most exciting and rapidly moving fields in contemporary biology. The 11th Gordon Conference on Cell Biology of the Neuron will be held on June 22-27, 2014 at Waterville Valley Resort, NH. This field is experiencing a revolution in both imaging technology and reporters for the analysis of cellular structure and physiology. There is an unprecedented ability to interrogate the intricate design and function of individual neurons and neural circuitry. At the same time, powerful molecular and genetic technologies are providing breakthrough mechanistic discoveries regarding neural development, plasticity, regeneration and disease. A stated goal of this meeting is to bring together leading scientists to present the most recent advances in this rapidly moving field. Relevance to human neurological disease will be addressed throughout the program, including presentations by prominent cell biologists working at the academic-industry interface, tackling the challenge of translating cell biological advances into therapeutics. Topics will focus on synapse formation, synaptic transmission, neural plasticity, membrane trafficking and transport, regeneration and degenerative disease. The conference will provide ample opportunities for junior scientists and graduate students to present their work. Members of under-represented minority groups are especially encouraged to attend. To ensure that the latest and most exciting results are presented, some poster presenters will be selected for short talks. The collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings, provides an avenue for scientists from different disciplines to brainstorm and promotes cross-disciplinary collaborations in the various research areas represented.