The 2014 Gordon Conference on Cellular and Molecular Fungal Biology (CMFB) will focus on the biology of fungi from the integrative perspective of cellular and molecular mechanisms, systems, and evolution at the Holderness School, an ideal venue for scientific interaction in a spectacular New England setting. The 2014 CFMB conference will continue in its tradition of collegial exchange among a diversity of attendees including graduate students, postdoctoral fellows, and PIs from university, government, and industrial laboratories. In sessions, late-breaking and unpublished research will be presented succinctly and balanced in approximately equal part by group discussion under the topics of: fungi in microbiomes, genome dynamics, development, cell biology, secretion and cell walls, fungi and biofuels, population and evolutionary genomics, symbiosis and pathogenicity, and a special session on late-breaking topics selected from the abstract submissions. In addition to the formal sessions in the mornings and evenings, there will be ample opportunity for informal exchange and recreation in the afternoons. The integrative theme will encourage substantive exchange among disciplines and ensure that the overall quality of the scientific experience will be higher than the sum of its component parts.