The 10th International Conference on Information Security Practice and Experience (ISPEC 2014) will be held in Fuzhou, China, May 5-8, 2014, and hosted by Fujian Provincial Key Laboratory of Network Security and Cryptology, Fujian Normal University (FNU), China. The ISPEC conference series is an established forum that brings together researchers and practitioners to provide a confluence of new information security technologies, including their applications and their integration with IT systems in various vertical sectors. In previous years, ISPEC has taken place in Singapore (2005), Hangzhou, China (2006), Hong Kong, China (2007), Sydney, Australia (2008), Xi'an, China (2009), Seoul, Korea (2010), Guangzhou, China (2011), Hangzhou, China (2012), and Lanzhou, China (2013). For all sessions, the conference proceedings were published by Springer in the Lecture Notes in Computer Science series.