Welcome to IEEE Cluster 2014. The conference will be held 22-26 September 2014 at the School of Industrial Engineering, UPM. Clusters have become the workhorse for computational science and engineering research, powering innovation and discovery that advance science and society. They are the base for building today's rapidly evolving cloud and HPC infrastructures, and are used to solve some of the most complex problems. Cluster 2014 welcomes paper submissions on innovative work from researchers and practitioners in academia, government, and industry that describe original research and development efforts in cluster computing.