The Second Guangzhou International Workshop on Mathematical Imaging will be held on December 14-15, 2013 in Sun Yat-sen University, Guangzhou, China. The objective of this workshop is to bring international experts in imaging together to present their recent research work, to exchange ideas, and to develop new visions for the future of the area. The workshop will provide an opportunity for participants to share information and experiences, and a platform for their research collaboration. On behalf of the organizing committee, it is my pleasure to invite interested researchers and professional experts to participate the workshop. Besides, we would like to express our appreciation to the following organizations for their generous sponsorships and support: 　 School of Mathematics and Computational Science, Sun Yat-sen University (中山大学数学与计算科学学院) Guangdong Province Key Laboratory of Computational Science (广东省计算科学重点实验室) Guangdong Provincial Computational Science Innovative Research Team (广东省计算科学引进创新团队) 　 We look forward to welcoming you in Guangzhou.