The Computational Science and Engineering area has earned prominence through advances in electronic and integrated technologies beginning in the 1940s. Current times are very exciting and the years to come will witness a proliferation in the use of various advanced computing systems. It is increasingly becoming an emerging and promising discipline in shaping future research and development activities in academia and industry, ranging from engineering, science, finance, economics, arts and humanitarian fields, especially when the solution of large and complex problems must cope with tight timing schedules. CSE 2013 is the next event, in a series of highly successful International Conferences on Computational Science and Engineering, held mainly as the International Workshop on High Performance Scientific and Engineering Computing for 10 editions, mostly in conjunction with International Conference on Parallel Processing (ICPP), as COATA-98 (Orlando, USA, July 1998), HPSEC-99 (Fukushima, Japan, September 1999), HPSEC-00 (Toronto, Canada, August 2000), HPSEC-01 (Valencia, Spain, September 2001), HPSEC-02 (Vancouver, Canada, August 2002), HPSEC-03 (Kaohsing, Taiwan, October 2003), HPSEC-04 (Montreal, Canada, August 2004), HPCSE-04 with WCC-04 (Toulouse, France, August 2004), HPSEC-05 (Oslo, Norway, June 2005), HPSEC-06 (Columbus, USA, August 2006) and CSE-08 (Sao Paulo, Brazil, July 2008). The previous CSE-09, CSE-10, CSE-11 and CSE-12 were held in Vancouver, Canada, August 29-31, 2009, Hong Kong, China, December 11-12, 2010, Dalian, China, August 24-26, 2011 and December 5-7, 2012, Paphos, Cyprus. CSE 2013 will take place in Sydney, Australia.