Intelligence and Security Informatics (ISI) research is an interdisciplinary research field involving academic researchers in information technologies, computer science, public policy, bioinformatics, medical informatics, and social and behavior studies, as well as local, state, and federal law enforcement and intelligence experts, information technology industry consultants and practitioners to support counterterrorism and homeland security missions of anticipation, interdiction, prevention, preparedness and response to terrorist acts. The annual IEEE International ISI Conference series (http://www.isiconference.org) was started in 2003. We invite academic researchers in the field of Intelligence and Security Informatics and related areas (such as computer science, public policy, and social and behavioral studies) as well as companies, industry consultants, analysts and practitioners in the fields involved. EISIC 2013 will be held in Uppsala, Sweden. Research should be relevant to applications of counter-terrorism or protection of local/national/international/global security in the physical world and/or cyberspace.