The International Symposium on Symbolic and Algebraic Computation is the premier conference for research in symbolic computation and computer algebra. ISSAC 2013 is the 38th meeting in the series. The conference traditionally presents a range of invited speakers, tutorials, poster sessions and software demonstrations with a centre-piece of contributed research papers. ISSAC 2013 will be held June 26-29, 2013 at Northeastern University, Boston, Massachusetts, USA For a map of the campus showing the buildings where the conference sessions will be held see VENUE