The increasing maturity, performance and miniaturization of sensors, interfaces, processors, networking technologies, memory and displays is enabling a move towards pervasive computing, ubiquitous connectivity and more adaptable interfaces that are sensitive and responsive. Many objects and devices already have embedded processors and sensors. Increasingly then, connections are not just people-people or people-computers, but between people-things and most strikingly, things-things. This changes the web from being a purely virtual, online space to a system that can provide appropriate information, help and services in the real world. If properly harnessed this information will make us better informed and enable smarter decisions by both people and machines. In this frame the range of applications is wide: from physics particle detection, industrial process control, automotive systems, space aircrafts, energy management to more recently biomedicine, and Brain Machine Interface. Although significant advances have been reported, many problems are still to be solved: system level design, design procedures, fabrication techniques and data handling and computing are open for research, while industrial interest is aiming at satisfying technological, cost and manufacturing requirements. The IEEE International Workshop on Advances in Sensors and Interfaces intends to provide a forum for exchange of experience among experts actively involved in research, development and evaluation of new concepts, theoretical methods and experimental characterization as well as in testing techniques concerning micro- and nano-sensor systems.