The Nitric Oxide (NO) Gordon Research Conference is designed to provide chemists, biologists, cell biologists, physiologists, clinicians and other scientists with state of the art knowledge on the basic concepts of NO and related bioactive nitrogen oxides as signaling molecules in physiological and pathophysiological states. The main strength of this meeting is the opportunity for cross disciplinary interactions and exploring new vistas in this important translational field of research. Invited speakers are encouraged to present their most recent findings and there will be ample discussion time scheduled after each talk. A particular focus for this meeting is to make a sincere effort to promote and showcase the work of young investigators. New works are also to be featured in a hot topics session and in two prominently featured poster sessions.