The International Conference of Applied Mathematics and Numerical Methods holds every two years at the University of Craiova and is organized by the Department of Applied Mathematics. Due to the exceptional conditions induced by the spread of the COVID 19 Pandemic, the fourth edition of ICAMNM 2022 will be a virtual - online - conference and it will be held between June 29 and July 2, 2022. The congress is mainly addressed to researchers, academic people, PhD students working in Applied and Pure Mathematics, Mathematical Biology, Mathematical Physics, Mathematical Engineering, Mathematical Economics, Mathematical Medicine, ODEs and PDEs, and Their Applications to Real World, Dynamical Systems, Control and Optimization, Algebra and Geometry, and Their Applications, Convex Analysis, Numerical Analysis and Their Applications. As joint event, a Workshop on Industrial Mathematics and Computer Science (second edition) will be held on July 2, 2022 and it will be mainly focused on presentations by persons working in Industry and academic institutions about the projects in which they were involved and used mathematical and computer science aspects.