Sample Abstract Template

1. Title: The Impact of Drug-target Binding Kinetics (maximum of 100 characters)

Name: XXXXX*

University of Applied Sciences, Darmstadt, Germany

2. Abstract Body (up to 250-300 words)
    

The importance of binding kinetics in terms of residence time and on-rate in drug discovery has been broadly accepted in the past few years. Furthermore, evidence has accumulated that the optimal binding mechanism of a drug to its target molecule is related to physiological efficacy as well as selectivity and thus drug safety. Homogeneous fluorescence-based binding assays have been shown to enable high throughput kinetics requiring only small amounts of protein. These assays can be used to elucidate even complex mechanisms of molecular recognition. A generalized approach is proposed that combines high quality kinetic and equilibrium data in an Integrated Global Fit analysis yielding the most probable binding mechanism. Arguments will be provided for the thesis that the relationship between quantitative kinetic and mechanistic information and chemical structures of active substances will serve as a valuable tool for drug optimization.

3. Biography:

XXXX has completed his PhD at the age of 25 years from XXXX University and Postdoctoral Studies from School of Medicine, XXXX University, Singapore. He is the Director of XXXX, a premier Bio-Soft service organization. He has published more than 25 papers in reputed journals and has been serving as an editorial board member of repute. (Up to 100-150 words)          

4. Presenting Author Details

Full Name:
Email-ID:
Contact Number:
Session Name:
Category: (Oral presentation/ Poster presentation)