SEED primarily focuses on research topics spanning across the boundaries of computer architecture, systems, and security. Papers are solicited on a range of topics, including (but not limited to):

- Architecture, operating systems, and programming models and language for supporting secure and private execution
- Novel Designs for secure and private execution environments for GPUs, accelerators, and FPGAs
- Architectural support for new security primitives
- Novel cryptographic hardware designs for secure and private execution
- Models and analysis of performance-security trade-offs in the design of a secure execution environment
- Evaluation of security vulnerabilities in post-Moore’s Law technologies, e.g. persistent memory, quantum computing
- Demonstration and mitigation of architectural side channels, covert channels and other security vulnerabilities
- Metrics for measuring architecture-related security vulnerabilities
- Compiler and code generation techniques for mitigating architecture-induced side and covert channels and other vulnerabilities