As part of the IEEE International Green and Sustainable Computing conference, a special workshop termed Energy-efficient Networks of Computers: from the Chip to the Cloud (E2NC) will be organized to address various design aspects of power efficient and dependable computing infrastructures from the perspective of the interconnection networks. Computing machinery around the world consumes staggering amounts of energy. The increasing power consumption of Integrated Circuits has plagued the semiconductor industry for years. Soaring power dissipations have proved to be the limiting factor for increase in performance. Complex digital integrated circuits consisting of multiple components or cores form the underlying hardware for these massive computing infrastructures. Warehouse-scale computers powered by such multicore chips have applications in several important domains ranging from scientific applications like weather or economic forecasting, astronomical data analysis, bioinformatics applications, to even consumer electronics. Graphics Processing Units (GPUs) and General Purpose GPUs (GPGPUs) and heterogeneous systems with CPUs, GPUs, memories, and programmable fabrics provide the computational backbone for not only graphics-based applications but many data parallel tasks as well. The Internet of Things (IoT) with billions of connected devices pose new challenges to the problem of connectivity and scale. All these computing infrastructures consist of interconnected or networked components. The role of the interconnection therefore becomes paramount in determining the performance and efficiency of these hardware. In addition, the reliability and security of these networked computing modules will also determine their sustainability and suitability in the near and distant future. This workshop will encompass a broad range of topics related to power efficiency and dependability of modern interconnected computing machinery at various scales from multicore chips to IoT, datacenters, and the cloud. Its objective is to facilitate exchange of valuable information and ideas among researchers and practitioners. The workshop will consist of invited presentations and peer-reviewed research papers.